SUSTAINED RELEASE DRUG DELIVERY DEVICE CONTAINING CODRUGS

摘要

This invention relates to sustained release drug delivery device containing codrugs that includes a polymer and a prodrug having solubility less than about 1 mg/ml dispersed in the polymer. Advantageously, the polymer is permeable to the prodrug and may be non-release rate limiting with respect to the rate of release of the prodrug from the polymer. This permits improved drug delivery within a body in the vicinity of a surgery via sustained release rate kinetics over a prolonged period of time, while not requiring complicated manufacturing processes.