发明名称 INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING VLA-4 VLA-4
摘要 The invention relates to compounds of formula I: wherein R1, R2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula I for use in the manufacture and delivery of conjugated moieties such as small molecules, peptides, nucleic acids, fluorescent moieties, and polymers which are linked to VLA-4 integrin antagonists to target cells expressing VLA-4.
申请公布号 HK1201472(A1) 申请公布日期 2015.09.04
申请号 HK20150102084 申请日期 2015.03.02
申请人 F. HOFFMANN-LA ROCHE AG 发明人 GOODNOW JR., ROBERT, ALAN;HAMILTON, MATTHEW, MICHAEL;SIDDURI, ACHYUTHARAO
分类号 A61K;A61P 主分类号 A61K
代理机构 代理人
主权项
地址