发明名称 |
INJECTABLE DEPOT FORMULATION COMPRISING OPTICALLY ACTIVE TOLVAPTAN AND PROCESS OF PRODUCING THE SAME |
摘要 |
This invention provides an injectable formulation to be administered intramuscularly or subcutaneously that is used for the prevention or treatment of polycystic kidney disease, and that can maintain a therapeutically effective blood concentration of tolvaptan for a long period of time; and a process for producing the same. More specifically, this invention relates to an injectable depot formulation comprising (1) a particle containing optically active tolvaptan as an active ingredient and (2) a pharmaceutically acceptable carrier for injection, and a process for producing the same. |
申请公布号 |
KR20150102083(A) |
申请公布日期 |
2015.09.04 |
申请号 |
KR20157020124 |
申请日期 |
2013.12.27 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
KANEKO DAIKI;MATSUDA TAKAKUNI;MIYATA KENICHI;SUZUKI KAI;FUJIKI HIROYUKI;KINOSHITA SHIZUO;OHMOTO KOJI;AIHARA MIKI |
分类号 |
A61K9/00;A61K9/10;A61K9/14;A61K9/16;A61K31/55 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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