| 发明名称 |
QUINOLINE COMPOUNDS |
| 摘要 |
The present invention relates to quinoline compounds as defined by Formula I below. Such quinoline compounds have been shown to inhibit the formation of amyloid deposits (e.g. amyloid oligomers, fibrils or plaques). Consequently, these compounds are suitably for treating a range of diseases and disorders in which amyloid deposits are implicated, such as type-2 diabetes and Alzheimer's disease. |
| 申请公布号 |
WO2015128674(A1) |
申请公布日期 |
2015.09.03 |
| 申请号 |
WO2015GB50588 |
申请日期 |
2015.02.27 |
| 申请人 |
ISIS INNOVATION LIMITED |
发明人 |
VAUX, DAVID;DEAN, LETITIA;DAVIES, STEPHEN;RUSSELL, ANGELA;WYNNE, GRAHAM;BATAILLE, CAROLE;BRENNAN, MÉABH |
| 分类号 |
C07D413/14;A61K31/47;A61K31/4709;A61P25/28;C07D215/26;C07D401/06 |
主分类号 |
C07D413/14 |
| 代理机构 |
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