| 发明名称 |
LYVE-1 ANTAGONISTS FOR PREVENTING OR TREATING A PATHOLOGICAL CONDITION ASSOCIATED WITH LYMPHANGIOGENESIS |
| 摘要 |
The present invention relates to the prevention or treatment of pathological conditions associated with lymphoangiogenesis (e.g. cancer and eye diseases). The present invention also relates to a method for screening for screening a compound capable of reducing or inhibiting lymphangiogenesis and which may be useful for preventing or treating a pathological condition associated with lymphangiogenesis. |
| 申请公布号 |
US2015246118(A1) |
申请公布日期 |
2015.09.03 |
| 申请号 |
US201314438465 |
申请日期 |
2013.10.24 |
| 申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ;UNIVERSITÉ DE BORDEAUX I |
发明人 |
Bikfalvi Andreas |
| 分类号 |
A61K39/395;C07K16/28;G01N33/50;A61K31/713;A61K45/06;C07K16/30;A61K38/17;C12N15/113 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for preventing or treating a pathological condition associated with lymphangiogenesis and/or for preventing tumor metastasis in a subject in need thereof comprising administering to said subject a therapeutically effective amount of a Lymphatic Vessel Endothelial Hyaluronan Receptor-1 (LYVE-1) antagonist. |
| 地址 |
Paris FR |
