VITAMIN D ANALOGUES FOR THE TREATMENT OF A NEUROLOGICAL DISORDER

摘要

Disclosed herein are methods that use a vitamin D analogue to treat a neurological disorder. Additionally, pharmaceutical compositions comprising a vitamin D analogue and a neurotherapeutic agent are disclosed, and methods of using the same. The pharmaceutical compositions and methods of the invention are useful for the treatment of a neurological disorder, for example, Alzheimer's disease, multiple sclerosis, Parkinson's disease, epilepsy, neuropathic pain, or other conditions that affect the central or peripheral nervous system of a subject.

主权项

1. A method of treating or reducing effects of a neurological disorder, the method comprising: administering a therapeutically effective amount of a vitamin D analogue, or a pharmaceutically-acceptable salt thereof, to a subject having symptoms of or diagnosed with a neurological disorder, wherein said effective amount of vitamin D analogue is one that does not exceed a threshold over which hypercalcemia is induced.