发明名称 |
Method for the prognosis and treatment of cancer metastasis |
摘要 |
<p>The present invention relates to a method for the prognosis of bone metastasis in cancer which comprises using a probe to determine if a gene of interest is amplified in a primary tumor sample. Likewise, the invention also relates to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise using a probe to determine the expression level of a gene of interest, or the amplification or translocation of a gene of interest. The invention also relates to a method for predicting early bone metastasis in a subject suffering cancer. The invention also relates to a c-MAF inhibitor as therapeutic agent for use in the treatment of cancer metastasis. The invention relates to kits for predicting bone metastasis and predicting the clinical outcome of a subject suffering from bone metastasis. Finally, the invention relates to a method for typing of a subject suffering cancer and for classifying a subject from cancer into a cohort.</p> |
申请公布号 |
AU2014229505(A1) |
申请公布日期 |
2015.09.03 |
申请号 |
AU20140229505 |
申请日期 |
2014.03.14 |
申请人 |
INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANCATS;FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA) |
发明人 |
GOMIS, ROGER;PLANET, EVARIST;PAVLOVIC, MILICA;ARNAL, ANNA;TARRAGONA, MARIA |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|