发明名称 |
Phosphoramidate derivatives of 5 - fluoro - 2 ' - deoxyuridine for use in the treatment of cancer |
摘要 |
Phosphoramidate derivatives of 5-fluoro-2'-deoxyuridine are disclosed for use in the treatment of cancer, especially in the treatment of cancer where the patient shows resistance, for example, in a patient with cells with a lowered level of nucleoside transporter proteins and/or with nucleoside kinase-deficient cells and/or with mycoplasma-infected cells and/or with cells with a raised level of thymidylate synthase. |
申请公布号 |
AU2012223012(C1) |
申请公布日期 |
2015.09.03 |
申请号 |
AU20120223012 |
申请日期 |
2012.02.29 |
申请人 |
NUCANA BIOMED LIMITED |
发明人 |
MCGUIGAN, CHRISTOPHER;BALZARINI, JAN;SLUSARCYZK, MAGDALENA;GONCZY, BLANKA;MURZIANI, PAOLA |
分类号 |
C07F9/6558;A61K31/675;A61P35/00 |
主分类号 |
C07F9/6558 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|