DISPENSING NEEDLE FOR A FRACTION COLLECTOR

摘要

Described is a dispensing needle for a fraction collector. The dispensing needle includes a conduit having a fluid channel to conduct a chromatographic system flow. The dispensing needle also includes a needle tip that has a fluid channel and an endface. The fluid channel of the needle tip is disposed at a dispensing end of the conduit and has a cross-sectional area that is less than a cross-sectional area of the fluid channel of the conduit. The fluid channels are in communication and enable a liquid chromatography system flow at a first velocity in the conduit to be dispensed at the endface of the needle tip at a second velocity that is greater than the first velocity. Advantageously, any droplets that may form at the endface of the needle tip are reduced in volume and therefore concentration variations for collected fractions are reduced.

主权项

1. A dispensing needle for a fraction collector, comprising:
a conduit defining a fluid channel for conducting a chromatography system flow, the fluid channel having a cross-sectional area; and a needle tip having a fluid channel and an endface, the fluid channel having a cross-sectional area that is less than the cross-sectional area of the fluid channel of the conduit, the needle tip disposed at a dispensing end of the conduit, wherein the fluid channels of the conduit and the needle tip are in fluidic communication to thereby enable a liquid chromatography system flow at a first velocity in the conduit to be dispensed at the endface of the needle tip at a second velocity that is greater than the first velocity.