| 发明名称 |
TREATMENT FOR NEURODEGENERATION |
| 摘要 |
Provided is a method of treating and/or preventing Wolfram Syndrome (WS)-related neurodegeneration (i.e. of Wolfram Syndrome-Associated Neuronal Degeneration), by increasing the expression and/or functional activity of p21. A method of screening for pharmacological agents useful in treating and/or preventing such conditions is also provided. |
| 申请公布号 |
US2015246037(A1) |
申请公布日期 |
2015.09.03 |
| 申请号 |
US201314431534 |
申请日期 |
2013.09.27 |
| 申请人 |
THE UNIVERSITY OF BIRMINGHAM |
发明人 |
Nagy Zsuzsanna;Barrett Timothy |
| 分类号 |
A61K31/496;A61K31/4706;A61K31/4439;A61K31/575;G01N33/50;A61K31/145;A61K31/451;A61K31/436;A61K31/192;A61K31/19;A61K31/4418 |
主分类号 |
A61K31/496 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound capable of increasing the expression and/or functional activity of p21 for use in the treatment and/or prevention of Wolfram Syndrome (WS)-related neurodegeneration. |
| 地址 |
Birmingham GB |
