Novel thiochromeno[2,3-c]quinolin-12-one derivatives, preparation method and application thereof

摘要

The invention provides a series of novel thiochromeno[2,3-c] quinolin-12-one derivatives. Further, the invention also provides the preparation method and application of said derivatives, said 5 application comprises: said derivatives with treating effective amount are prepared into pharmaceutical compositions for inhibition of topoisomerase type I and II, inhibition of cancer cell growth, further treating cancer.