发明名称 |
ALK ANTIBODIES, CONJUGATES, AND CHIMERIC ANTIGEN RECEPTORS, AND THEIR USE |
摘要 |
Chimeric antigen receptors that specifically bind to anaplastic lymphoma kinase are disclosed. Nucleic acids, recombinant expression vectors, host cells, antibodies, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed. |
申请公布号 |
WO2015069922(A3) |
申请公布日期 |
2015.09.03 |
申请号 |
WO2014US64383 |
申请日期 |
2014.11.06 |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
ORENTAS, RIMAS;MACKALL, CRYSTAL |
分类号 |
C07K14/725;C07K16/30;C07K16/46 |
主分类号 |
C07K14/725 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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