| 发明名称 | Method and composition for enhancing cognition in alzheimer's patients | ||
| 摘要 | The invention relates to a pharmacologically active combination and a method of enhancing cognitive performance in a patient suffering from Alzheimer's disease comprising administering to said patient a cognitive performance-enhancing amount of melatonin or a melatonin agonist in a combination therapy with a nicotine receptor agonist. | ||
| 申请公布号 | US9119846(B2) | 申请公布日期 | 2015.09.01 |
| 申请号 | US201414482160 | 申请日期 | 2014.09.10 |
| 申请人 | Neurim Pharmaceuticals (1991) Ltd. | 发明人 | Zisapel Nava;Laudon Moshe |
| 分类号 | A61K31/445;A61K31/4045;A61K31/13;A61K9/24;A61K45/06;A61K9/20;A61K9/70;A61K31/27;A61K31/465;A61K31/55 | 主分类号 | A61K31/445 |
| 代理机构 | Rothwell, Figg, Ernst & Manbeck, P.C. | 代理人 | Rothwell, Figg, Ernst & Manbeck, P.C. |
| 主权项 | 1. A method of enhancing cognitive performance in a patient suffering from Alzheimer's Disease comprising administering to said patient a cognitive performance-enhancing amount of about 2 mg melatonin in a combination therapy with 5, 10 or 23 mg donepezil. | ||
| 地址 | Tel Aviv IL | ||