Redox processes for contact lens modification

摘要

Medical devices having a wettable, biocompatible surface are described herein. Processes for producing such devices are also described.

主权项

1. A process for modifying the surface of a silicon-containing hydrogel, the process comprising the steps of:
forming a reaction mixture comprising the silicon-containing hydrogel, a polymerization monomer, a free radical initiator system and a solvent system, the polymerization monomer comprising a zwitterionic monomer and the free radical initiator system comprising a peroxide in the presence of a metal ion; and polymerizing the polymerization monomer in the reaction mixture to form a surface modification polymer on the surface of the silicon-containing hydrogel, wherein the silicon-containing hydrogel does not undergo a plasma treatment and is not imbibed with an initiator or monomer.