发明名称 |
HIG2 and URLC10 epitope peptide and vaccines containing the same |
摘要 |
The present invention provides a pharmaceutical agent or composition containing one or more peptides having the amino acid sequence of SEQ ID NO: 1 or 2, or one or more polynucleotides encoding such a peptide formulated for the treatment and/or prevention of cancer in a subject whose HLA-A antigen is HLA-A0206. Furthermore, the present invention provides a method of inducing CTL and antigen-presenting cells using such peptides, polynucleotides or pharmaceutical agents. |
申请公布号 |
US9119800(B2) |
申请公布日期 |
2015.09.01 |
申请号 |
US200913059618 |
申请日期 |
2009.08.14 |
申请人 |
OncoTherapy Science, Inc. |
发明人 |
Tsunoda Takuya;Ohsawa Ryuji;Yoshimura Sachiko |
分类号 |
A61K39/385;A61K39/00;C07K14/725;A61K38/00 |
主分类号 |
A61K39/385 |
代理机构 |
Kilpatrick Townsend & Stockton LLP |
代理人 |
Kilpatrick Townsend & Stockton LLP |
主权项 |
1. A method for inducing an antigen-presenting cell with high CTL inducibility, wherein the method comprises the steps of
a) collecting APCs from a subject whose HLA-A antigen is HLA-A0206, and b) contacting the APCs of step a with a peptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NO: 1 and 2. |
地址 |
Kanagawa JP |