发明名称 |
Protein exhibiting human interferon-like biological activities, isolated polynucleotide encoding same, recombinant vector comprising said isolated polynucleotide and host cell containing said recombinant vector |
摘要 |
<p>This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-±2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer.</p> |
申请公布号 |
IL196673(A) |
申请公布日期 |
2015.08.31 |
申请号 |
IL20090196673 |
申请日期 |
2009.01.22 |
申请人 |
NOVAGEN HOLDING CORPORATION |
发明人 |
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分类号 |
C12N |
主分类号 |
C12N |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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