摘要 |
The invention relates to biparatopic A-beta binding polypeptides and, more specifically, to biparatopic A-beta binding polypeptides comprising at least two immunoglobulin single variable domains binding to different epitopes of A-beta. The invention also relates to specific sequences of such polypeptides, methods of their production, and methods of using them, including methods of treatment of diseases such as Alzheimer's Disease. |
申请人 |
ABLYNX N.V. |
发明人 |
PARK, JOHN, E.;DORNER-CIOSSEK, CORNELIA;HOERER, STEFAN;KUSSMAUL, LOTHAR;LENTER, MARTIN;ZIMMERMANN, KATHARINA;BESTE, GERALD;LAEREMANS, TOON;MERCHIERS, PASCAL;VERCAMMEN, JO |