A PROCESS FOR PREPARING METHACRYLIC ACID OR METHACRYLIC ESTERS

摘要

THE PRESENT INVENTION RELATES TO A PROCESS FOR THE PREPARATION OF METHACRYLIC ACID OR METHACRYLIC ESTERS, COMPRISING THE PROCESS STEPS OF IA) PREPARATION OF 3-HYDROXYISOBUTYRIC ACID BY A PROCESS COMPRISING THE PROCESS STEP OF BRINGING A CELL WHICH HAS BEEN GENETICALLY MODIFIED IN COMPARISON WITH ITS WILD TYPE IN SUCH A WAY THAT IT IS CAPABLE OF FORMING MORE 3-HYDROXYISOBUTYRIC ACID, OR POLYHYDROXYALKANOATES BASED ON 3-HYDROXYISOBUTYRIC ACID IN COMPARISON WITH ITS WILD TYPE, INTO CONTACT WITH A NUTRIENT MEDIUM COMPRISING, AS CARBON SOURCES, CARBOHYDRATES, GLYCEROL, CARBON DIOXIDE, METHANOL, L-VALINE OR L-GLUTAMATE UNDER CONDITIONS UNDER WHICH 3-HYDROXYISOBUTYRIC ACID OR POLYHYDROXYALKANOATES BASED ON 3-HYDROXYISOBUTYRIC ACID ARE FORMED FROM THE CARBON SOURCES, IF APPROPRIATE, ISOLATION OF THE 3-HYDROXYISOBUTYRIC ACID FROM THE NUTRIENT MEDIUM AND ALSO, IF APPROPRIATE, NEUTRALIZATION OF THE 3-HYDROXYISOBUTYRIC ACID, IB) DEHYDRATION OF THE 3-HYDROXYISOBUTYRIC ACID WITH FORMATION OF METHACRYLIC ACID AND ALSO, WHERE APPROPRIATE, ESTERIFICATION METHACRYLIC ACID. THE INVENTION ALSO RELATES TO A PROCESS FOR THE PREPARATION OF POLYMETHACRYLIC ACID OR POLYMETHACRYLIC ESTERS.