发明名称 System For Dispensing A Sample Into a Buffer Liquid
摘要 A system for dispensing a sample (5) into a buffer liquid comprises a pressure chamber (1) having pressure supply means for generating an overpressure within the pressure chamber. An inlet capillary (2) is provided for supplying a buffer liquid (9) to an outlet end (6) arranged in the pressure chamber. Also, an outlet capillary (3) is provided for discharging buffer liquid and/or sample from the pressure chamber. The outlet capillary (3) has an inlet end (7) arranged in the pressure chamber (1) facing the outlet end (6) of the inlet capillary (2) to form a capillary gap (8). A dispenser (4) having a dispensing end (10) is arranged in the pressure chamber (1) at the capillary gap (8) to allow the sample (5) at the dispensing end (10) to be dispensed from the dispensing end (10) into the buffer liquid entering the inlet end (7) of the outlet capillary (3). The pressure chamber (1) comprises a pressure-tight sample port (13) adapted to allow the dispenser (4) with the dispensing end (10) to be moved into and out of the pressure chamber (1), wherein the pressure chamber (1) comprises a pressure-tight sample port adapted to allow the dispenser (4) with the dispensing end (10) to be moved into and out of the pressure chamber (1).
申请公布号 US2015238966(A1) 申请公布日期 2015.08.27
申请号 US201314426360 申请日期 2013.09.06
申请人 F. Hoffmann-La Roche AG 发明人 Berndt Peter;Fattinger Christof;Steiner Roger
分类号 B01L3/00 主分类号 B01L3/00
代理机构 代理人
主权项 1. A system for dispensing a sample, in particular a liquid sample, into a buffer liquid, the system comprising: a pressure chamber having pressure supply means for generating an overpressure within the pressure chamber relative to a pressure outside the pressure chamber, an inlet capillary for supplying a buffer liquid to an outlet end of the inlet capillary, the outlet end of the inlet capillary being arranged in the pressure chamber, an outlet capillary for discharging the buffer liquid and/or the sample from the pressure chamber, the outlet capillary having an inlet end being arranged in the pressure chamber in a manner such that the outlet end of the inlet capillary and the inlet end of the outlet capillary are facing each other to form a capillary gap allowing the buffer liquid exiting the outlet end of the inlet capillary to cross the capillary gap and enter the inlet end of the outlet capillary and a dispenser having a dispensing end which, during dispensing of the sample, is arranged in the pressure chamber at the capillary gap to allow the sample to be dispensed from the dispensing end into the buffer liquid entering the inlet end of the outlet capillary, wherein the pressure chamber comprises a pressure-tight sample port adapted to allow the dispenser with the dispensing end to be moved into and out of the pressure chamber.
地址 Basel CH