发明名称 |
IL-2RBETA-SELECTIVE AGONISTS IN COMBINATION WITH AN ANTI-CTLA-4 ANTIBODY OR AN AN ANTI-PD-1 ANTIBODY |
摘要 |
The invention relates to (among other things) method of administering to a patient suffering from a cancer, the method comprising the steps of: (a) an IL-2Rβ-activating amount of a long acting, IL-2Rβ-selective agonist; and (b) a CTLA-4 pathway-inhibiting amount of an anti-CTLA-4 antibody or a PD-1 pathway-inhibiting amount of an anti-PD-1 antibody. |
申请公布号 |
WO2015125159(A1) |
申请公布日期 |
2015.08.27 |
申请号 |
WO2015IN00099 |
申请日期 |
2015.02.20 |
申请人 |
NEKTAR THERAPEUTICS (INDIA) PVT. LTD.;NEKTAR THERAPEUTICS |
发明人 |
ADDEPALLI, MURALI KRISHNA;CHARYCH, DEBORAH H.;KANTAK, SEEMA;LEE, STEVEN ROBERT |
分类号 |
A61K45/06;A61K38/20;A61K39/395;A61K47/48;A61P35/00 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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