| 发明名称 |
NAPHTHYLAMIDE COMPOUND, PREPARATION METHOD AND USE THEREOF |
| 摘要 |
The present invention relates to a naphthylamide compound of the structure as represented by formula (I), medicinal salts, prodrugs and hydrates or solvates thereof, and also relates to a method of preparing the compounds, pharmaceutical compositions comprising the compounds and the uses thereof as protein tyrosine kinase inhibitors, particularly as VEGFR-2 inhibitors, in preparing drugs for preventing and treating diseases related to abnormal angiogenesis. |
| 申请公布号 |
WO2015124101(A1) |
申请公布日期 |
2015.08.27 |
| 申请号 |
WO2015CN73121 |
申请日期 |
2015.02.15 |
| 申请人 |
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES |
发明人 |
DUAN, WENHU;DING, JIAN;LV, YONGCONG;XIE, HUA |
| 分类号 |
C07D231/56;A61K31/416;A61K31/422;A61K31/423;A61K31/4355;A61K31/4365;A61K31/4439;A61K31/519;A61P17/06;A61P27/02;A61P29/00;A61P35/00;C07D261/20;C07D491/048;C07D495/04 |
主分类号 |
C07D231/56 |
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