| 发明名称 |
Inhibition of tissue factor pathway inhibitor with factor Xa derivatives |
| 摘要 |
<p>The present disclosure relates to compositions and methods for the treatment of bleeding disorders, such as hemophilia A, hemophilia B, von Willebrand (vWF) disease, and factor XII deficiency, by reducing the circulating concentration of tissue factor pathway inhibitor (TFPI), with a factor Xa derivative.</p> |
| 申请公布号 |
AU2013375294(A1) |
申请公布日期 |
2015.08.27 |
| 申请号 |
AU20130375294 |
申请日期 |
2013.03.13 |
| 申请人 |
PORTOLA PHARMACEUTICALS, INC. |
发明人 |
LU, GENMIN;SINHA, UMA;KARBARZ, MARK;PANDEY, ANJALI;CONLEY, PAMELA B. |
| 分类号 |
C07K14/745;A61K38/48;A61K47/48;C12N9/64 |
主分类号 |
C07K14/745 |
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