发明名称 METHOD FOR ISOLATING FRACTION HAVING ANTI-INFLAMMATORY OR OSTEOARTHRITIS-INHIBITING EFFECTS BY USING OYSTER SHELL CHIPS
摘要 The present invention relates to a method for isolating a fraction having anti-inflammatory or osteoarthritis-inhibiting effects by removing impurities and washing oyster shells, which are produced during a process of producing oysters, drying same, forming a powder from the oyster shells, and adding anhydrous citric acid to same for a reaction, obtaining a reaction product, and isolating a supernatant, which is obtained by centrifugally separating the reaction product, by means of ultrafiltration. By adding the anhydrous citric acid to the oyster shell chips for the reaction at a relatively low temperature, the present invention provides superior advantages, such as significantly reducing energy costs and isolating the fraction having the anti-inflammatory or osteoarthritis inhibiting effects through a simple method.
申请公布号 US2015238542(A1) 申请公布日期 2015.08.27
申请号 US201214429321 申请日期 2012.12.17
申请人 SEOJIN BIOTECH CO., LTD. 发明人 Kim Hak-Ju;Han Ji-Sook;Byoun Yeoun-Ju
分类号 A61K35/618;B01D61/14;B01D21/26 主分类号 A61K35/618
代理机构 代理人
主权项 1. A method for isolating a fraction having an anti-inflammatory effect using oyster shell, characterized in that the said method comprises: a) a preliminary step of removing foreign materials attached to the oyster shell, washing the oyster shell with water and then drying and grinding the washed oyster shell to make a powder; b) a reaction step of reacting the oyster shell powder obtained from the said preliminary step with an anhydrous citric acid to obtain a reaction product; c) a supernatant-recovering step of centrifuging the reaction product obtained from the said reaction step to recover a supernatant; and d) an isolation step of isolating the supernatant obtained from the said supernatant-recovering step using ultra-filtration membrane and then drying the same to isolate a fraction having an anti-inflammatory effect.
地址 Gyeonggi-do KR