发明名称 |
Enantiopure tetrasubstituted pyrrolidines as scaffolds for proteasome inhibitors and medicinal applications thereof |
摘要 |
<p>The present invention refers to compounds of general formula (I):
as well as to a method for their preparation, pharmaceutical compositions comprising the same, and the use thereof for the treatment and/or chemoprevention of cancer, hematological malignancy, proliferative diseases, autoimmune diseases, neurodegenerative diseases and viral infections.</p> |
申请公布号 |
EP2910557(A1) |
申请公布日期 |
2015.08.26 |
申请号 |
EP20140382058 |
申请日期 |
2014.02.20 |
申请人 |
IKERCHEM, S.L.;UNIVERSIDAD DEL PAIS VASCO |
发明人 |
COSSIO MORA, FERNANDO PEDRO;RETAMOSA HERNANDEZ, MARÍA DE GRACIA;LARUMBE GARATA, AMAIA;ZUBIA OLASCOAGA, AIZPEA;BELLO IGLESIAS, TAMARA;VARA SALAZAR, YOSU ION;MASDEU MARGALEF, MARÍA DEL CARMEN;ALDABA AREVALO, ENEKO |
分类号 |
C07F5/02;A61K31/69;A61P35/00 |
主分类号 |
C07F5/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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