| 发明名称 |
Tumor necrosis factor inhibitors |
| 摘要 |
<p>The present invention is directed to compounds that are allosteric inhibitors of tumor necrosis factor receptor I, compositions comprising such compounds, and methods of using such compounds and compositions thereof in the treatment of TNF-± mediated conditions.</p> |
| 申请公布号 |
EP2305246(B1) |
申请公布日期 |
2015.08.26 |
| 申请号 |
EP20100010595 |
申请日期 |
2006.01.31 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
GREENE, MARK I.;MURALLI, RAMACHANDRAN;CHENG, XIN;OTTENBRITE, RAPHAELE;XIAO, YINGXIN |
| 分类号 |
A61K31/365;A61K31/15;A61K31/352;C07C69/035 |
主分类号 |
A61K31/365 |
| 代理机构 |
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