| 发明名称 |
Cdna mutante e infeccioso do vírus da febre amarela, constructo de dna, vírus recombinante de febre amarela e vacina para humanos contra infecções de febre amarela. |
| 摘要 |
<p>The present invention is related to a vaccine composition for humans against YF infections consisting essencially of a recombinant YF virus, YFiv5.2/DD, which is regenerated from YF infectious cDNA. There is provided new plasmids, pYF 5'3' IV/G1/2 and pYFM 5.2/T3/27, which together, have the complete sequence of said YF infectious cDNA. The method for producing recombinant YF virus and the Original, Primary and Secondary Seed Lots are other embodiments of the present invention. <IMAGE></p> |
| 申请公布号 |
BRPI9701774(B1) |
申请公布日期 |
2015.08.25 |
| 申请号 |
BR19979701774 |
申请日期 |
1997.04.11 |
| 申请人 |
FUNDAÇÃO OSWALDO CRUZ (FIOCRUZ) |
发明人 |
RICARDO GALLER;MARCOS DA SILVA FREIRE |
| 分类号 |
A61K39/12;C12N15/40;A61K39/00;C07K14/08;C07K14/18;C12N7/00;C12N7/01 |
主分类号 |
A61K39/12 |
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