Preventive or therapeutic agent for pain associated with herpes zoster in acute phase

摘要

A P2X4 receptor antagonist such as paroxetine, a diazepinedione derivative having the following formula (IX) is used as an agent for preventing or treating zoster-associated pain in acute phase:;
wherein R1 is hydrogen, a C1-8 alkyl group, or the like;
each of R2 and R3 is hydrogen, a C1-8 alkyl group, or the like;each of R4 and R5 is hydrogen or the like; andW is a five-membered or six-membered heterocyclic ring optionally having one or more substituents and comprising one to four nitrogen atoms as the members of the ring.

主权项

1. A method of treating prodrome or pain of herpes zoster in acute phase comprising administrating an effective amount of P2X4 receptor antagonist to a patient in need thereof.