发明名称 |
Methods for sustained treatment of bladder pain and irritative voiding |
摘要 |
Method are provided for treating a patient having bladder pain and/or irritative voiding symptoms. The method includes administering to the patient's bladder lidocaine or another anesthetic agent continuously over a treatment period of 24 hours or more in an amount effective to achieve a therapeutic effect which is sustained beyond the end of the treatment period. |
申请公布号 |
US9114111(B2) |
申请公布日期 |
2015.08.25 |
申请号 |
US201213347513 |
申请日期 |
2012.01.10 |
申请人 |
Allergan, Inc. |
发明人 |
Himes Julie;Giesing Dennis;Larrivee-Elkins Cheryl;Cima Michael J.;Sarma Purnanand;Goldenheim Paul |
分类号 |
A61M31/00;A61K31/167;A61K9/00 |
主分类号 |
A61M31/00 |
代理机构 |
Sutherland Asbill & Brennan LLP |
代理人 |
Sutherland Asbill & Brennan LLP |
主权项 |
1. A method of treating a patient having bladder pain and/or irritative voiding symptoms, the method comprising:
administering to the patient's bladder an agent, which comprises lidocaine, continuously over a treatment period of 24 hours or more in an amount effective to achieve a therapeutic effect which is sustained beyond an end of the treatment period, wherein the lidocaine is released into the bladder at a rate of from 15 mg to 30 mg lidocaine (FBE) per day over a first 1 to 4 days of the treatment period and then tapers to a rate of from 15 mg to 3 mg lidocaine (FBE) per day over a remainder of the treatment period. |
地址 |
Irvine CA US |