发明名称 System and method for perfusing biological organs
摘要 A system for perfusing a biological organ for use as an experimental model includes a housing having sides that define a cavity for containing a biological organ model within a solution. The housing includes a plurality of apertures defined therethrough configured to mechanically interface with a filter, one or more heating elements and one or more sensors. A peristaltic pump is configured to withdraw and pressurize the solution from the housing and reintroduce the solution under pressure into the biological organ. A heat control module operatively connects to the heating elements and is configured to regulate the temperature of the solution within the housing. A data acquisition system operatively connects to the heat control module, the peristaltic pump and the sensor(s) and regulates and monitors the pressure, flow rate and temperature of the solution during electrical treatment of the biological organ.
申请公布号 US9113624(B2) 申请公布日期 2015.08.25
申请号 US200812251857 申请日期 2008.10.15
申请人 Covidien LP 发明人 Belous Anna;McMunigal Tom E.;Podhajsky Ronald J.;Hammond Jeffrey A.
分类号 A01N1/00;A01N1/02 主分类号 A01N1/00
代理机构 代理人
主权项 1. A system for perfusing a biological organ for use as an experimental model, the system comprising: a housing having sides that define a cavity for containing a biological organ within a solution, the housing including a plurality of apertures defined therethrough configured to mechanically interface with at least one heating element and at least one sensor; a removable conductive ground plate disposed in the housing, the removable conductive ground plate including a plurality of legs extending therefrom and configured to provide a return path during radiofrequency electrical treatment of the biological organ; a specimen table for supporting the biological organ within the housing, the specimen table including a plurality of legs extending therefrom and configured to nestingly-receive the removable conductive ground plate below the specimen table; a peristaltic pump configured to withdraw the solution from the housing and reintroduce the solution under pressure into the biological organ; a heat control module operatively connected to the at least one heating element, the heat control module configured to regulate the temperature of the solution within the housing; and a data acquisition system operatively connected to the heat control module, the peristaltic pump and the at least one sensor, the data acquisition system configured to regulate the pressure, flow rate and temperature of the solution during electrical treatment of the biological organ, the data acquisition system includes a computer for analyzing data received from the at least one sensor, heat control module and peristaltic pump.
地址 Mansfield MA US