发明名称 Salt of abexinostat, associated crystalline form, a process for their preparation and pharmaceutical compositions containing them
摘要 Abexinostat tosylate of formula (II):; and its crystalline form I characterized by its X-Ray powder diffraction diagram, its Raman spectrum and its solid-state 13C CP/MAS NMR spectrum. ;Medicinal products containing the same which are useful in the treatment of cancer.
申请公布号 US9115108(B2) 申请公布日期 2015.08.25
申请号 US201414195186 申请日期 2014.03.03
申请人 PHARMACYCLICS, INC. 发明人 Pimont-Garro Anne;Letellier Philippe
分类号 C07D307/85;C07C309/30 主分类号 C07D307/85
代理机构 Hueschen and Sage 代理人 Hueschen and Sage
主权项 1. A crystalline form I of abexinostat tosylate of formula (II):having an X-ray powder diffraction diagram having the following diffraction lines (Bragg's angle 2 theta, expressed in degrees ±0.2°): 6.50, 9.94, 11.35, 12.33, 14.08, 18.95, 21.08, and 27.05.
地址 Sunnyvale CA US
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