| 发明名称 |
Processo para a fabricação de moduladores de regulador de condutância de transmembrana de fibrose cística |
| 摘要 |
The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent. |
| 申请公布号 |
BRPI1011506(A2) |
申请公布日期 |
2015.08.25 |
| 申请号 |
BR2010PI11506 |
申请日期 |
2010.03.19 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
JOHN DEMATTEI;ADAM R. LOOKER;BOBBIANNA NEUBERT-LANGILLE;MARTIN TRUDEAU;STEFANIE ROEPER;MICHAEL P. RYAN;DAHRIKA MILFRED LAO YAP;BRIAN R. KRUEGER;PETER D. J. GROOTENHUIS;FREDERICK F. VAN GOOR;MARTYN C. BOTFIELD;GREGOR ZLOKARNIK |
| 分类号 |
C07D215/233 |
主分类号 |
C07D215/233 |
| 代理机构 |
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