| 摘要 |
PROBLEM TO BE SOLVED: To provide a medicament that is effective in the treatment of cancer by inhibiting the activity of type I and II topoisomerase.SOLUTION: Provided is a derivative, medically acceptable salt, stereoisomer and enantiomer of thiochromeno[2,3-c]quinolin-12-one shown in the following formula. (R is a Cl, hydroxy group, methoxy group, dimethylamino group, substituted or unsubstituted piperazin-1-yl group, morpholino group, thiomorpholino group, substituted or unsubstituted piperidin-1-yl group, or a substituted alkyl group, etc.). |
