发明名称 COMPOSITIONS AND METHODS THAT UTILIZE A PEPTIDE TAG THAT BINDS TO HYALURONAN
摘要 <p>The invention relates, in part, to compositions and methods that utilize a peptide tag that binds to hemagglutanin (HA). The HA tag can be linked to a molecule such as a protein or nucleic acid which, when administered to the eye, results in an increase in ocular half-life and/or mean residence time, and or a decrease in ocular clearance of the protein or nucleic acid. The invention also encompasses methods for treating ocular disease, including retinal vascular disease, by administering a protein or nucleic acid linked to an HA peptide tag.</p>
申请公布号 KR20150095684(A) 申请公布日期 2015.08.21
申请号 KR20157015849 申请日期 2013.12.17
申请人 NOVARTIS AG 发明人 GHOSH JOY;ROGUSKA MICHAEL;NGUYEN ANDREW ANH;GOLOSOV ANDREI;PIETZONKA THOMAS;MACHACEK MATTHAIS
分类号 A61K47/48;A61K9/00;A61K39/395;A61K47/42;C07K14/47;C07K16/22 主分类号 A61K47/48
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