| 摘要 |
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to transplantology, and can be applied for monitoring the patient's condition after organ transplantation. For this purpose, after transplantation monitoring of the redox potential (RP) of the patient's blood plasma is carried out. RP of the patient's blood plasma is daily determined by a platinum electrode relative to a silver chloride electrode. The platinum electrode is preliminarily processed by means of cathode-anode scanning in a solution of an inorganic reducing agent in a cyclic potential-dynamic mode. Daily monitoring of RP value of the patient's blood plasma is carried out and changes of RP values in one direction within a day or some days are identified. If the change of RP of more than 25 mV per day or several days is determined, a conclusion about the presence of transplant dysfunction or a high risk of development of a transplant rejection crisis is made. In case of detection of the RP value change less than 25 mV, a conclusion about the normal condition of the patient is made.EFFECT: invention makes it possible to realise the prediction of transplantation outcome and provide the timely correction of the patients' treatment.1 tbl, 4 ex, 3 dwg |
