发明名称 |
Proceso de reducción asimétrica |
摘要 |
<p>The present invention relates to a stereoselective reduction procedure to obtain, by means of catalytic asymmetric hydrogenation by hydrogen transfer, a compound of formula (I) in which X is S or SO2 and R4 is hydrogen or an SO2NH2 group, from the corresponding ketone precursor, said compound of formula (I) being useful as an intermediate in the preparation of dorzolamide or of the hydrochloride salt thereof.</p> |
申请公布号 |
ES2543643(T3) |
申请公布日期 |
2015.08.20 |
申请号 |
ES20120709828T |
申请日期 |
2012.03.08 |
申请人 |
ZACH SYSTEM S.P.A. |
发明人 |
VOLPICELLI, RAFFAELLA;ANDRETTO, MAURO;COTARCA, LIVIUS;NARDI, ANTONIO;VERZINI, MASSIMO |
分类号 |
C07D495/04 |
主分类号 |
C07D495/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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