发明名称 |
LATEX PARTICLES FOR PARTICLE AGGLUTINATION ASSAY |
摘要 |
A particulate latex for high-sensitive agglutination assay that barely poses non-specific reactions and can readily prepare diagnostic reagents, and a reagent for agglutination assay including the particle are provided. A particulate latex for agglutination assay, including a first polymerizable monomer having a phenyl group, a second polymerizable monomer having a phenyl group and a salt of sulfonic acid, and a third polymerizable monomer represented by Formula (1):;CH2═CR1—COOCH2CH2O(PO2)OCH2CH2—N(CH3)3 (1);where R1 represents a hydrogen atom or a methyl group,
wherein the density of functional groups in the third polymerizable monomer represented by Formula (1) on the surface of the particulate latex is 0.003 to 0.05 μmol/m2. |
申请公布号 |
US2015233906(A1) |
申请公布日期 |
2015.08.20 |
申请号 |
US201314431555 |
申请日期 |
2013.09.27 |
申请人 |
SEKISUI MEDICAL CO., LTD. |
发明人 |
Kitahara Shinichiro;Takahashi Yuki |
分类号 |
G01N33/545;C08L33/14 |
主分类号 |
G01N33/545 |
代理机构 |
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代理人 |
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主权项 |
1. A particulate latex for agglutination assay, comprising:
a first polymerizable monomer having a phenyl group; a second polymerizable monomer having a phenyl group and a salt of sulfonic acid; and a third polymerizable monomer represented by Formula (1):
CH2═CR1—COOCH2CH2O(PO2)OCH2CH2—N(CH3)3 (1)where R1 represents a hydrogen atom or a methyl group,
wherein the density of functional groups of the third polymerizable monomer represented by Formula (1) on the surface of the particulate latex is 0.003 to 0.05 μmol/m2. |
地址 |
Chuo-ku, Tokyo JP |