发明名称 INHIBITING PEPTIDES DERIVED FROM TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS-1 (TREM-1) TREM-LIKE TRANSCRIPT 1 (TLT-1) AND USES THEREOF
摘要 The present invention relates to a peptide comprising at least 6 consecutive amino acid selected from the amino acid sequence SEQ ID NO: 2 and a function-conservative variant. The invention also relates to a peptide comprising at least 6 consecutive amino acid selected from the amino acid sequence SEQ ID NO: 1 or SEQ ID NO: 2 and a function-conservative variant for use in the treatment of a cardiovascular disease.
申请公布号 US2015232531(A1) 申请公布日期 2015.08.20
申请号 US201314426562 申请日期 2013.09.09
申请人 INSERM (Institut National de la Santé et de la Recherche Médicale) ;UNIVERSITÉ DE LORRAINE 发明人 Gibot Sebastien;Boufenzer Amir;Ait-Oufella Hafid;Derive Marc
分类号 C07K14/705 主分类号 C07K14/705
代理机构 代理人
主权项 1. A method for treating a cardiovascular disease comprising administering a peptide comprising at least 6 consecutive amino acids selected from the amino acid sequence SEQ ID NO: 1 or SEQ ID NO: 2 and a function-conservative variant thereof.
地址 Paris Cedex 13 FR