| 摘要 |
FIELD: medicine.SUBSTANCE: invention relates to the field of genetic engineering and medicine. Claimed method of treating neurodegenerative diseases and Alzheimer's disease, including intranasal introduction to the subject of a therapeutically effective quantity of YB-1 protein, possessing an amino acid sequence of human SEQ ID NO:1 or rabbit SEQ ID NO:7 and/or its active fragment separately or in a composition, which additionally contains one or several agents, which enhance the intranasal delivery of the composition to the brain.EFFECT: invention ensures the efficiency of low doses of the protein, reduction of side effects, as well as a possibility of applying the highly-purified genetically-engineered protein.6 cl, 8 dwg, 4 ex |
