发明名称 TREATMENT OF HEART FAILURE WITH NORMAL EJECTION FRACTION
摘要 PROBLEM TO BE SOLVED: To provide a method of treating the heart failure with normal left ventricular (LV) ejection fraction (HFnEF).SOLUTION: The invention relates to perhexiline (2-(2,2-dicyclohexylethyl)piperidine), or a pharmaceutically acceptable salt thereof, for use in the treatment of HfnEF, and to a method for treating HFnEF, which comprises administering to an animal in need thereof an effective amount of perhexiline, or a pharmaceutically acceptable salt thereof, to treat HFnEF. The invention further relates to a treatment program for treating HFnEF, which involves the co-use or co-administration of perhexiline with one or more other compounds that are advantageous in treating HFnEF or symptoms thereof.
申请公布号 JP2015147787(A) 申请公布日期 2015.08.20
申请号 JP20150075231 申请日期 2015.04.01
申请人 HEART METABOLICS LTD 发明人 HOUMAN ASHRAFIAN;MICHAEL PAUL FRENNEAUX
分类号 C07D211/12;A61K31/4458;A61K45/00;A61P9/04 主分类号 C07D211/12
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