发明名称 ISOQUINOLINE DERIVATIVES AND USE THEREOF
摘要 The Invention provides compounds of Formula (I) and pharmaceutically acceptable salts, solvates, hydrates, N-oxides, or diastereomers thereof: wherein W1, W2, W3, J1, J2, A, R1, R2, R3, R4, R5, a, and b are defined as set forth in the specification. The Invention also provides uses of the compounds of any one of Formulae (I)- (VIII) and the pharmaceutically acceptable salts, solvates, hydrates, N-oxides, or diastereomers thereof. Compounds of the Invention are useful for treating a disorder responsive to blockade of one or more sodium channels. In certain embodiments, Compounds of the Invention are useful for treating pain.
申请公布号 CA2939501(A1) 申请公布日期 2015.08.20
申请号 CA20152939501 申请日期 2015.02.12
申请人 PURDUE PHARMA L.P. 发明人 TAFESSE, LAYKEA;PARK, JAE HYUN
分类号 C07D401/04;A61K31/4725;A61P25/00;A61P29/00;C07D401/14;C07D403/04 主分类号 C07D401/04
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