KIT AND METHOD FOR QUANTITATIVE DETECTION OF STEROIDS

摘要

The invention relates to a kit and methods for quantitative detection of steroids in a sample. The kit comprises quantitative charge tags and an oxidising agent.

主权项

1. A kit for detecting steroids comprising:
i. at least one pair of quantitative charge tags based on a compound of formula (I) or a compound of formula (II): wherein R is hydrogen, C1-4 alkyl or aryl, OR1 or NR1R2;
each R1 and R2 is C1-3 alkyl or R1 and R2 together with the nitrogen atom to which they are attached form a 5- or 6-membered heteroalkyl ring; and each R3 is independently C1-3 alkyl; X is a halide ion; and ii. an agent capable of oxidising an OH group at the steroid 3-position to a ketone.