| 主权项 |
1. An L-nucleic acid molecule that binds an SDF-1, wherein the L-nucleic acid molecule comprises in 5′→3′ direction, a first stretch of nucleotides, a core nucleotide sequence and a second stretch of nucleotides,
wherein the core nucleotide sequence comprises GGUYAGGGCUHRXAAGUCGG (SEQ ID NO: 90), wherein XA either is absent or is A; and the first stretch of nucleotides comprises 5′ RKSBUSNVGR 3′ (SEQ ID NO:120) and the second stretch of nucleotides comprises 5′ YYNRCASSMY 3′ (SEQ ID NO:121); or the first stretch comprises 5′ XSSSSV 3′ (SEQ ID NO:124) and the second stretch comprises 5′ BSSSXS 3′ (SEQ ID NO:125), wherein XS either is absent or is S; or the first stretch comprises 5′ UGAGAUAGG 3′ (SEQ ID NO:94) and the second stretch comprises 5′CUGAUUCUCA 3′ (SEQ ID NO:212); or the first stretch comprises 5′ GAGAUAGG 3′ (SEQ ID NO:94) and the second stretch of nucleotides comprises 5′ CUGAUUCUC 3′ (SEQ ID NO:212). |
