| 摘要 |
Methods of determining a source of, and/or tracking the transmission of, an organism, including pathogenic organisms. Processor-readable medium having processor-executable instructions for performing such methods. Systems for tracking the path of an infection. Electronic systems for tracking the transmission of a pathogen. Methods for determining regions of DNA suitable for one-way analysis. Infection Control Analysis Decision Systems comprising a processing device in communication with memory containing instructions for carrying out methods of determining a source of, and/or tracking the transmission of, an organism, including pathogenic organisms. |
| 主权项 |
1. A method of determining a source of, and/or tracking the transmission of, a pathogenic organism, the method comprising:
receiving, in a processing device, laboratory test results representing partial or complete nucleotide sequence or expression state data for a pathogenic organism in a first biological sample and in a second biological sample, comparing, by a processing device, a genetic state data for the organism in the first biological sample to a genetic state data for the organism in the second biological sample; determining, by the processing device, whether the first and second nucleotide sequence or expression states have a one-away relationship based on the partial or complete nucleotide sequence or expression state data for the pathogenic organism in the first biological sample and in the second biological sample; recording, in memory in communication with the processing device, the relationship between the organism in the first and second biological samples if the first and second nucleotide sequences or expressions are the same or one-away; and constructing, by the processing device, a representation of the transmission of the pathogenic organism based on connections between samples containing organisms having a one-away relationship. |
