| 发明名称 |
SUSTAINED RELEASE SMALL MOLECULE DRUG FORMULATION |
| 摘要 |
An injectable depot formulation includes a biocompatible polymer, an organic solvent combined with the biocompatible polymer to form a viscous gel, and a small molecule drug incorporated in the viscous gel such that the formulation exhibits an in vivo release profile having Cmax to Cmin ratio less than 200 and lag time less than 0.2. |
| 申请公布号 |
US2015231258(A1) |
申请公布日期 |
2015.08.20 |
| 申请号 |
US201514701173 |
申请日期 |
2015.04.30 |
| 申请人 |
DURECT CORPORATION |
发明人 |
LUK Andrew S.;JUNNARKAR Gunjan H.;CHEN Guohua |
| 分类号 |
A61K47/34;A61K31/519;A61K9/00;A61K31/341 |
主分类号 |
A61K47/34 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An injectable depot formulation, comprising:
a biocompatible polymer; an organic solvent combined with the biocompatible polymer to form a viscous gel; and a small molecule drug incorporated in the viscous gel such that the formulation exhibits an in vivo release profile having Cmax to Cmin ratio less than 200 and lag time less than 0.2. |
| 地址 |
Cupertino CA US |
