发明名称 |
RECOMBINANT STRAIN PRODUCING L-AMINO ACIDS, CONSTRUCTING METHOD THEREFOR AND METHOD FOR PRODUCING L-AMINO ACIDS. |
摘要 |
Provided is a recombinant strain producing L-amino acids, a constructing method therefor and a method for producing L-amino acids. Compared with the starting strains, the recombinant strain producing L-amino acids has decreased expression of 6-phosphoglucose isomerase Pgi and increased expression of 6-phosphogluconate dehydrogenase Zwf-OpcA. The starting strain can accumulate objective amino acids. Fermentation culturing of the recombinant strain can increase the yield of L-amino acids significantly. Also provided is a novel method for increasing the fermentation yield of L-amino acids, capable of being be used in bacterial fermentation of L-amino acids. |
申请公布号 |
WO2015120775(A1) |
申请公布日期 |
2015.08.20 |
申请号 |
WO2015CN72220 |
申请日期 |
2015.02.04 |
申请人 |
INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES |
发明人 |
WEN, TINGYI;SHANG, XIULING;ZHANG, YUN;LIU, SHUWEN;LIANG, YONG;ZHANG, YU |
分类号 |
C12N1/21;C12P13/24;C12R1/15 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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