发明名称 |
OLIGONUCLEOTIDE-CONTAINING PHARMACOLOGICAL COMPOSITIONS AND THEIR USE |
摘要 |
The present invention relates to methods and compositions containing oligonucleotides suitable for administration to humans and other mammals. |
申请公布号 |
US2015232857(A1) |
申请公布日期 |
2015.08.20 |
申请号 |
US201414534901 |
申请日期 |
2014.11.06 |
申请人 |
LAKEWOOD-AMEDEX, INC. |
发明人 |
DALE RODERIC M.K.;ARROW AMY;Thompson Teresa |
分类号 |
C12N15/113;A61Q19/00;A61K8/60 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
1. A composition suitable for administration in a mammal comprising a modified oligonucleotide of about seven to seventy-five nucleotides containing seven or more contiguous ribose groups linked by achiral 5′ to 3′ internucleoside phosphate linkages, wherein the modified oligonucleotide is complementary to a region of a gene associated with a pathological disorder. |
地址 |
SARASOTA FL US |