SYSTEM FOR OPTIMAL MECHANICAL VENTILATION

摘要

The invention relates to a system for mechanical ventilation comprising transducers for measurement of airway flow rate, pressure and CO2 and at least one computer that records and analysis the transducer signals. The operator defines physiological specified goals or accepts default values. Specified physiological goals relate to CO2 exchange and to volumes and pressures so as to minimise deleterious effects of ventilation. On the basis of physiological information about the respiratory system characterised according to the principle of volumetric capnography and lung mechanical parameters, the computer performs analytical calculations in order to identify one or more modes of ventilator operation leading to specified goals. Such a mode of operation is implemented manually or automatically in one or more steps. The physiological outcome of resetting is reported and an alarm is issued when the outcome deviates from expectations. The computer may perform repeated automatic measurements and repeat the resetting in order to reach and maintain a status of the patient coherent with specified goals.

主权项

1. A system for mechanical ventilation comprising:
transducers for measurement of flow rate and CO2; and a computer that records and analyses the transducer signals according to the principle of volumetric capnography, wherein the computer is programmed for analytic mathematical analysis of data recorded before a ventilator resetting in order to identify one or more alternative combinations of values describing a mode of ventilator operation, which combinations comprise at least tidal volume and respiratory frequency, and which are predicted to lead to achievement of specified goals representing one or more of the parameters comprising arterial partial pressure of CO2, arterial pH and tidal volume, which identification is performed with calculations based upon a measured volume of CO2 eliminated per minute or other unit of time, a measured content of CO2 in expired alveolar gas and a change of volume of CO2 eliminated per breath that a change of current tidal volume is calculated to bring about.