发明名称 |
BENZIMIDAZOL-2-AMINES AS MIDH1 INHIBITORS |
摘要 |
The present invention relates to benzimidazol-2-amines of general formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients. |
申请公布号 |
CA2939026(A1) |
申请公布日期 |
2015.08.20 |
申请号 |
CA20152939026 |
申请日期 |
2015.02.10 |
申请人 |
BAYER PHARMA AKTIENGESELLSCHAFT |
发明人 |
REHWINKEL, HARTMUT;PANKNIN, OLAF;RING, SVEN;ANLAUF, SONJA;SIEBENEICHER, HOLGER;NGUYEN, DUY;SCHWEDE, WOLFGANG;BAUSER, MARCUS;ZIMMERMANN, KATJA;KAULFUSS, STEFAN;NEUHAUS, ROLAND;BLANEY, PAUL MATTHEW |
分类号 |
C07D235/30;A61K31/4184;A61P35/00 |
主分类号 |
C07D235/30 |
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