发明名称 |
BIFUNCTIONAL CONJUGATE COMPOSITIONS AND ASSOCIATED METHODS |
摘要 |
Conjugates comprising a N-oxime bond are disclosed. In one embodiment, a suitable conjugate is represented by the following Formula (I): wherein R′ is derived from a compound comprising at least one reactive amide group, R″ is derived from a compound comprising at least one reactive aminooxy group, and X is H, CnH(n+2) or other atoms. Additional methods are also provided. |
申请公布号 |
EP2585096(A4) |
申请公布日期 |
2015.08.19 |
申请号 |
EP20110798980 |
申请日期 |
2011.06.24 |
申请人 |
UNIVERSITY OF KANSAS |
发明人 |
BERKLAND, CORY;SESTAK, JOSHUA;SIAHAAN, TERUNA, J. |
分类号 |
A61K38/16;A61K39/00;A61K39/385;A61K47/48;C07B43/00 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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