| 发明名称 |
SOLID FORMS OF NILOTINIB HYDROCHLORIDE |
| 摘要 |
Disclosed are solid forms of Nilotinib hydrochloride and methods of preparation of various crystalline solvates of Nilotinib HCl including benzyl alcohol, acetic acid, propylene glycol, and isopropanol. Nilotinib HCl is a tyrosine kinase inhibitor used for the treatment of drug resistant chronic myelogenous leukemia (CML). |
| 申请公布号 |
EP2906554(A1) |
申请公布日期 |
2015.08.19 |
| 申请号 |
EP20130846872 |
申请日期 |
2013.10.15 |
| 申请人 |
APOTEX INC. |
发明人 |
DATTA, PROBAL KANTI;ZETINA-ROCHA, CARLOS;MCPHAIL, CAMERON L.;ZHAO, YAJUN;WEERATUNGA, GAMINI |
| 分类号 |
C07D401/14;A61K31/506;A61P35/02 |
主分类号 |
C07D401/14 |
| 代理机构 |
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